International Symposium
Physical Biology of Multicellular Dynamics

March 12 - 13, 2026 MIRAICHI Research Center, Kanazawa University

OVERVIEW

Outline

Multicellular dynamics— key process by which the functions and forms of tissues, organs, and entire organisms are shaped— have long been, and continue to be, one of the central focuses for researchers working at the intersection of biology and physics. This symposium aims to highlight recent advances in understanding various aspects of such multicellular dynamics through the lens of physics, covering topics such as cell-cell interactions, morphogenesis, tissue organization, and multiscale cell mechanics.

Organizers

Tetsuya Hiraiwa (Institute of Physics, Academia Sinica)
Satoru Okuda (Nano Life Science Institute, Kanazawa Univ.)

Date & Time

March 12, 2026, 9:30 AM – March 13, 2026, 1:30 PM

Venue

MIRAICHI Research Center, 3rd Floor
Kanazawa University
Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan
► See the access

Language

English

Registration Fee

Free of charge

Acknowledgments

NanoLSI Transformative Research A

PROGRAM

Speakers

  1. Chen-Hui Chen (Institute of Cellular and Organismic Biology, Academia Sinica)
  2. Antoine Diez (RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences)
  3. Natalie Dye (Mechanobiology Institute, National University of Singapore)
  4. Takeshi Fukuma (Nano Life Science Institute, Kanazawa University)
  5. Chin-lin Guo (Institute of Physics, Academia Sinica)
  6. Sayuki Hirano (Graduate School of Biostudies, Kyoto University)
  7. Tsuyoshi Hirashima (Mechanobiology Institute, National University of Singapore)
  8. Fumio Motegi (Institute for Genetic Medicine, Hokkaido University)
  9. Shizue Ohsawa (Graduate School of Science, Nagoya University)
  10. Alice Tsuboi (RIKEN Center for Biosystems Dynamics Research)
  11. Hiroyuki Uechi (Graduate School of Pharmaceutical Sciences, Kyoto University)
  12. Yu-Chiun Wang (RIKEN Center for Biosystems Dynamics Research)
  13. Tetsuya Hiraiwa (Institute of Physics, Academia Sinica)
  14. Satoru Okuda (Nano Life Science Institute, Kanazawa University)

Time Table

Thursday, March 12
TimeSpeakers
8:45 -Venue opens
9:00 -Registration opens
9:30 - 10:40
(Chair: Tsuyoshi Hirashima)
Opening Remarks: Satoru Okuda
Satoru Okuda, Nano LSI, Kanazawa Univ.
Elastoplastic transition and mechanical feedback during epithelial morphogenesis
Alice Tsuboi, RIKEN BDR
Instructive roles of the extracellular matrix in buckling-based tissue morphogenesis
Coffee Break
11:00 - 12:10
(Chair: Alice Tsuboi)
Shizue Ohsawa, Graduate School of Science, Nagoya Univ.
Non-autonomous ECM disassembly drives the epithelial shape transition of the Drosophila wing discs
Natalie Dye, Mechanobiology Institute, NUS
3D morphogenesis of the Drosophila wing disc
Lunch Break & Poster Viewing
13:10 - 14:20
(Chair: Natalie Dye)
Chen-Hui Chen, ICOB, Academia Sinica
What can we learn from monitoring every single cell in a living fish?
Fumio Motegi, IGM, Hokkaido Univ.
Cooperative induction of oogenesis via cytoplasmic suction from developing oocytes
Coffee Break
14:40 - 15:50
(Chair: Chen-Hui Chen)
Yu-Chiun Wang, RIKEN BDR
Morphogenetic arms race: how might mechanics influences evolution
Sayuki Hirano, Graduate School of Biostudies, Kyoto Univ.
Dynamic redistribution of adhesion-related molecules tunes collective cell behavior
Coffee Break
16:10 - 17:20
(Chair: Sayuki Hirano)
Hiroyuki Uechi, Graduate School of Pharmaceutical Sciences, Kyoto Univ.
Sidekick condensation ensures protein accumulation to tricellular junctions for epithelial remodeling
Takeshi Fukuma, Nano LSI, Kanazawa Univ.
Visualizing nanoscale dynamics and mechanics in living cells by nanoendoscopy AFM
Break
17:30 - 20:30
(Chair: Tetsuya Hiraiwa)
Poster Session & Banquet
Welcome Remarks: Takeshi Fukuma, Nano LSI, Kanazawa Univ.
Welcome Remarks: Fumio Motegi, IGM, Hokkaido Univ.
Friday, March 13
TimeSpeakers
9:00 -Venue opens
9:30 - 10:40
(Chair: Hiroyuki Uechi)
Chin-lin Guo, Institute of Physics, Academia Sinica
Creating Scaffold-Free Mimetic Environments within Scaffolds to Scale Up Cell Self-Organization
Tsuyoshi Hirashima, Mechanobiology Institute, NUS
Waves, order, and flow emerging from mechanochemical coupling in active epithelia
Coffee Break & Poster Viewing
11:10 - 12:20
(Chair: Chin-lin Guo)
Antoine Diez, RIKEN iTHEMS
Self-organized mechano-chemical instabilities drive the emergence of tissue morphogenesis in digit organoids
Tetsuya Hiraiwa, Institute of Physics, Academia Sinica
In silico study of morphogenesis of dynamic cell assemblies
12:20 - 12:25Closing Remarks: Tetsuya Hiraiwa
12:25 - 13:30Lunch with Free Discussion (Posters off the boards)
13:30 - 14:30Tour of NanoLSI (Registration required)

POSTER SESSION

Poster Session Information

Maximum poster size: Up to 170 cm (H) × 120 cm (W)
(e.g., A0 portrait, 841 mm × 1189 mm)
Mounting time: By lunchtime on Day 1
Presentation time (author attendance): TBA

Poster List (tentative)

No.NameAffiliationTitle
01Abhinandan AngraRIKEN BDRSpontaneous Symmetry Breaking in Confined Actomyosin
02Alexis BorowiakKanazawa Univ.Ferroelectric Cell Culture Substrates: A Biomechanical Study
03Chan Chung WingKyoto Univ.Active Polar Swarms in Heterogeneous Alignment Fields: Theory, Simulation, and Experiment
04Basnayake Kavindu DeshanKanazawa Univ.Development of Phthalocyanine-Based Photothermal Dyes for Localized Heating at the Plasma Membrane
05Nada DouguiRIKEN BDRThe Importance of Spectrin in Epithelial Apical Dome Maintenance and Dorsal Fold Initiation
06Dam Truyen DucNagoya Univ.How Chirality Stabilizes Dense Active Matter
07Hironobu FujiwaraRIKEN BDRMolecular and biophysical insights into basement membrane remodelling in mammalian epithelial morphogenesis
08Shuya FukamachiKanazawa Univ.Mechanical instability inherent in foam geometry induces epithelial stratification
09Kana FurukawaUOsakaElucidating the Principles of Tracheal Tissue Formation Driven by Epithelial–Mesenchymal Mechanical Interactions
10Jun HatakeyamaKumamoto Univ.Direct Measurement of Intraventricular Pressure in Developing Mouse Embryos
11Masayoshi HayashiNagoya Univ.Myoblast Migration and Epithelial Morphological Changes Regulated by Basement Membrane ECM Dynamics
12Lisna HidayatiNAISTPredicting Single-Cell Movement from Surrounding Cells' ERK Activity Using Machine Learning during Wound Healing
13Hiroshi HosoiNagoya Univ.Deciphering the Mechanisms of Epithelial Deformation in the Drosophila Wing Imaginal Disc
14Kohji HottaKeio Univ.Residual Tail Twisting in Ascidian Larvae Is Stabilized by Asymmetric Myofibrils Against Bilateral Symmetry Restoration
15Ryunosuke KarimataKanazawa Univ.An antiparallel cell circulation driven by self-aligned tension gradient
16Li CuiCuiKanazawa Univ.Observation of the calcium wave that propagates the developing Drosophila compound during cellular mechanical interaction
17Anshuman MishraRIKEN BDRExploration of a mechanosensitive link between tissue-scale mechanical instabilities and subcellular remodeling of epithelial polarity during Drosophila dorsal fold formation
18Nguyen Thi Nhu YKanazawa Univ.Fluorescence lifetime–based biosensor for quantifying temperature in living cells
19Rena OgawaKeio Univ.Live Imaging Analysis of Mesenchymal Cells during Ascidian Metamorphosis
20Phan Minh TriKanazawa Univ.A red color fluorescence lifetime-based ATP biosensors working at 37 ℃
21Ren WeichaoKanazawa Univ.Dynamics of the radial actin fibers in the developing Drosophila compound eye during cellular mechanical interaction
22Yuichi SakumuraNAISTMachine Learning Analysis of Determinants of Endothelial Cell Migration Direction in Angiogenesis
23Makoto SatoKanazawa Univ.More Than Just Hexagons: Does an Einstein Tile Exist in Life?
24Tatsuo ShibataRIKEN BDRCollective chiral behaviors of multicellular systems
25Aska SonokiShiseido Co., LTD.Low-Level Compressive Force Reorganizes Collagen Fiber Orientation and Enhances Dermal Strength
26Aki TeranishiKanazawa Univ.Mechanosensitive Elastoplastic Transition in Epithelial Folding Ensures Unidirectional Morphogenesis
27Chayanit ThiticharoentamKanazawa Univ.Computational Design of Epithelial Architectures via Modulation of Cell–Cell Interfacial Tension in a 3D Vertex Model
28Hisaaki TsutsumiNIBBComparative Proteomics of the Endometrial Apical Surface to Identify Essential Factors for Successful Implantation
29Valentina TyukosovaKanazawa Univ.A divergent pattern of long-term cell shape and motility arising from a tensile gradient of a nonconservative fluid membrane

BANQUET

Banquet

Date & Time: March 12, from 6:00 PM
Venue: Same location as the symposium
Fee: 4,000 yen (registration required; via the registration form)

REGISTRATION

How to Register

Please register using the following form.
► Registration Form

Registration Deadline

Saturday, January 31, 2026 (JST)
Sunday, February 8, 2026 (JST)
Closed

Registration Fee

Free of charge

VENUE

Lunch

Fee: 1,000 yen for each day (registration required; via the registration form)
  1. There are only a limited number of places nearby to have lunch, so we recommend ordering a lunch box through the registration form.
  2. The cost of the lunch box will be advanced by the conference, and therefore no changes can be made after registration.

Accomodation

Participants are kindly requested to arrange their own accommodation.
As there are few hotels near the venue, we recommend staying in the downtown "Korinbo" area, such as:

Wi-Fi

eduroam is available throughout the venue.
Please set up eduroam with your home institution in advance. For configuration instructions, refer to your institution's guide.

ACCESS

Access

The venue, Kanazawa University Kakuma Campus, is located a bit away from the train station and downtown area. Transportation by bus or taxi is required.
MIRAICHI Research Center, Kanazawa University
Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan


Komatsu Airport ⇔ Kanazawa Station (by Bus)

  • Duration & Fee: approx. 55 min, 1,300 yen
  • Take the Hokuriku Railway Limousine Bus running between Komatsu Airport.
  • Get off at Kanazawa Station (West Gate).

Kanazawa Station / Korinbo (Downtown) ⇔ MIRAICHI Research Center (by Taxi)

  • Duration & Fee: approx. 25 minutes, approx. 3,500 yen
  • From Station: Take a taxi from the "Kenrokuen-guchi (East Gate)" taxi stand.
  • From Korinbo: Take a taxi from a nearby taxi stand or on the street.
  • Tell the driver: "Kanazawa University, Kakuma Campus, MIRAICHI Research Center".
    If not understood, please say: "Nano Life Science Institute (ナノ生命科学研究所)" or "Cancer Research Institute (がん進展制御研究所)".

Kanazawa Station ⇔ Kanazawa University Kakuma Campus (by Bus)

  • Duration & Fee: approx. 32 minutes, 380 yen
  • From Station: Take bus No. 93, 94, or 97 bound for "Kanazawa University (Kakuma Campus)" from "Kenrokuen-guchi (East Gate) Bus Terminal" (Bus Stop No. 8). Get off at "Kanazawa University Institute of Natural Science".
  • Return trip: From the same stop ("Kanazawa University Institute of Natural Science"), take bus No. 93, 94, or 97 back to Kanazawa Station.

Korinbo (Downtown) ⇔ Kanazawa University Kakuma Campus (by Bus)

  • Duration & Fee: approx. 22 minutes, 380 yen
  • From Korinbo: Take bus No. 93, 94, 96, or 97 bound for "Kanazawa University (Kakuma Campus)" from "Shiko Kinenkan-mae" (四高記念館前, in front of Ishikawa Shiko Memorial Park) (Bus Stop No. 1). Get off at "Kanazawa University Institute of Natural Science".
  • Return trip: From the same stop ("Kanazawa University Institute of Natural Science"), take bus No. 93, 94, 96, or 97 back to Korinbo.

Note: Kanazawa University Kakuma Campus is different from Kanazawa University Hospital. Please be sure to head to the Kakuma Campus (Institute of Natural Science area), not the hospital.


Bus Station ⇔ MIRAICHI Research Center (by Walk)

  • Duration: less than 10 min
・Pass through buildings inner course
・Pass outside outer course

CONTACT

Contact

Please use the form below to contact us.
► Contact Form